Preparation and evaluation of lipid-based sustained release pellets of chlorpheniramine maleate by the wet extrusion-spheronization method

Preparation and evaluation of lipid-based sustained release pellets of chlorpheniramine maleate by the wet extrusion-spheronization method

Introduction: This study aimed to investigate the feasibility of preparation of sustained-release chlorpheniramine maleate (CPM) pellets based on Compritol® as a lipid matrix and evaluation of the affecting factors on pellet properties. Methods: Using the D-optimal experimental design, different pel...

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Bibliographic Details
Main Authors: Mohammadreza Abbaspour, Asieh Sadooghi, Elham Khodaverdi, Hossein Shahdadi Sardou, Ali Nokhodchi
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2024-07-01
Series:BioImpacts
Subjects:
sustained-release systems
chlorpheniramine maleate
compritol®
wet extrusion-spheronization
matrix pellet
Online Access:https://bi.tbzmed.ac.ir/PDF/bi-15-30098.pdf

Internet

https://bi.tbzmed.ac.ir/PDF/bi-15-30098.pdf

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