External lysis of Escherichia coli by a bacteriophage endolysin modified with hydrophobic amino acids

Abstract Drug-resistant bacteria are a serious threat to global public health. Gram-positive bacterial endolysin preparations have been successfully used to fight Gram-positive bacteria as a novel antimicrobial replacement strategy. However, Gram-negative bacterial phage endolysins cannot be applied...

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Bibliographic Details
Main Authors: Guangmou Yan, Rui Yang, Kejia Fan, Hanlin Dong, Chencheng Gao, Shuang Wang, Ling Yu, Zhe Cheng, Liancheng Lei
Format: Article
Language:English
Published: SpringerOpen 2019-07-01
Series:AMB Express
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13568-019-0838-x