Mathematical modeling of pneumococcal transmission dynamics in response to PCV13 infant vaccination in Germany predicts increasing IPD burden due to serotypes included in next-generation PCVs

Mathematical modeling of pneumococcal transmission dynamics in response to PCV13 infant vaccination in Germany predicts increasing IPD burden due to serotypes included in next-generation PCVs

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<h4>Introduction</h4> Two next-generation pneumococcal conjugate vaccines (PCVs), a 15- and a 20-valent PCV (PCV15 and PCV20), have recently been licensed for use in adults, and PCV15 has also been licensed in children. We developed a dynamic transmission model specific for Germany, with...

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Bibliographic Details
Main Authors: Matthias Horn, Christian Theilacker, Ralf Sprenger, Christof von Eiff, Ernestine Mahar, Julia Schiffner-Rohe, Mathias W. Pletz, Mark van der Linden, Markus Scholz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9931105/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9931105/?tool=EBI

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