Current Understanding of <i>DDX41</i> Mutations in Myeloid Neoplasms

The DEAD-box RNA helicase 41 gene, <i>DDX41</i>, is frequently mutated in hereditary myeloid neoplasms, identified in 2% of entire patients with AML/MDS. The pathogenesis of <i>DDX41</i> mutation is related to the defect in the gene’s normal functions of RNA and innate immuni...

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Bibliographic Details
Main Authors: Kunhwa Kim, Faustine Ong, Koji Sasaki
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/15/2/344