Current Understanding of <i>DDX41</i> Mutations in Myeloid Neoplasms
The DEAD-box RNA helicase 41 gene, <i>DDX41</i>, is frequently mutated in hereditary myeloid neoplasms, identified in 2% of entire patients with AML/MDS. The pathogenesis of <i>DDX41</i> mutation is related to the defect in the gene’s normal functions of RNA and innate immuni...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-01-01
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Series: | Cancers |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6694/15/2/344 |