mCRP-Induced Focal Adhesion Kinase-Dependent Monocyte Aggregation and M1 Polarization, Which Was Partially Blocked by the C10M Inhibitor

mCRP-Induced Focal Adhesion Kinase-Dependent Monocyte Aggregation and M1 Polarization, Which Was Partially Blocked by the C10M Inhibitor

Monomeric C-reactive protein (mCRP) has recently been implicated in the abnormal vascular activation associated with development of atherosclerosis, but it may act more specifically through mechanisms perpetuating damaged vessel inflammation and subsequent aggregation and internalization of resident...

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Bibliographic Details
Main Authors: Ylenia Pastorello, Doina Manu, Xenia Sawkulycz, Vittorio Caprio, Claudia Banescu, Minodora Dobreanu, Lawrence Potempa, Mario Di Napoli, Mark Slevin
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:International Journal of Molecular Sciences
Subjects:
macrophage M1 polarization
mCRP
inflammation
vascular activation
small molecule inhibitors
Online Access:https://www.mdpi.com/1422-0067/25/6/3097

Internet

https://www.mdpi.com/1422-0067/25/6/3097

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