Differential critical residues on the overlapped region of the non-structural protein-1 recognized by flavivirus and dengue virus cross-reactive monoclonal antibodies

Differential critical residues on the overlapped region of the non-structural protein-1 recognized by flavivirus and dengue virus cross-reactive monoclonal antibodies

Abstract The non-structural protein-1 (NS1) of dengue virus (DENV) contributes to several functions related to dengue disease pathogenesis as well as diagnostic applications. Antibodies against DENV NS1 can cross-react with other co-circulating flaviviruses, which may lead to incorrect diagnosis. He...

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Bibliographic Details
Main Authors: Prasit Luangaram, Chamaiporn Tamdet, Chananya Saengwong, Tanapan Prommool, Romchat Kraivong, Napon Nilchan, Nuntaya Punyadee, Panisadee Avirutnan, Chatchawan Srisawat, Prida Malasit, Watchara Kasinrerk, Chunya Puttikhunt
Format: Article
Language:English
Published: Nature Portfolio 2022-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-26097-y

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https://doi.org/10.1038/s41598-022-26097-y

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