Quiescent Cancer Cells—A Potential Therapeutic Target to Overcome Tumor Resistance and Relapse
Quiescent cancer cells (QCCs) are nonproliferating cells arrested in the G0 phase, characterized by ki67<sup>low</sup> and p27<sup>high</sup>. QCCs avoid most chemotherapies, and some treatments could further lead to a higher proportion of QCCs in tumors. QCCs are also associ...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-02-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/24/4/3762 |