Mitochondrial Activity and Unfolded Protein Response are Required for Neutrophil Differentiation

Mitochondrial Activity and Unfolded Protein Response are Required for Neutrophil Differentiation

Background/Aims: Endoplasmic reticulum (ER) stress and unfolded protein response (UPR) are involved in hematopoietic differentiation. However, the mechanistic linkage between ER stress/UPR and hematopoietic differentiation remains unclear. Methods: We used bipotent HL-60 cells as an in vitro hematop...

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Bibliographic Details
Main Authors: Ayako Tanimura, Keiko Miyoshi, Taigo Horiguchi, Hiroko Hagita, Koichi Fujisawa, Takafumi Noma
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-07-01
Series:Cellular Physiology and Biochemistry
Subjects:
ATP
ER stress
HL-60
Mitochondria
Myelocytic differentiation
Unfolded protein response
Online Access:https://www.karger.com/Article/FullText/491464

Internet

https://www.karger.com/Article/FullText/491464

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