Pectenotoxin-2 from Marine Sponges: A Potential Anti-Cancer Agent—A Review

Pectenotoxin-2 (PTX-2), which was first identified as a cytotoxic entity in marine sponges, has been reported to display significant cytotoxicity to human cancer cells where it inhibits mitotic separation and cytokinesis through the depolymerization of actin filaments. In the late stage of endoredup...

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Bibliographic Details
Main Authors: Wun-Jae Kim, Yung Hyun Choi, Gi-Young Kim
Format: Article
Language:English
Published: MDPI AG 2011-11-01
Series:Marine Drugs
Subjects:
Online Access:http://www.mdpi.com/1660-3397/9/11/2176/