Dopamine Transporter Knockout Rats Display Epigenetic Alterations in Response to Cocaine Exposure

Dopamine Transporter Knockout Rats Display Epigenetic Alterations in Response to Cocaine Exposure

(1) Background: There is an urgent need for effective treatments for cocaine use disorder (CUD), and new pharmacological approaches targeting epigenetic mechanisms appear to be promising options for the treatment of this disease. Dopamine Transporter (DAT) transgenic rats recently have been proposed...

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Bibliographic Details
Main Authors: Samara Vilca, Claes Wahlestedt, Sari Izenwasser, Raul R. Gainetdinov, Marta Pardo
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Biomolecules
Subjects:
cocaine
DAT
knockout
epigenetics
KDM6B
BRD4
Online Access:https://www.mdpi.com/2218-273X/13/7/1107

Internet

https://www.mdpi.com/2218-273X/13/7/1107

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