Synopsis of the pharmacokinetics, pharmacodynamics, applications, and safety of firocoxib in horses
According to in vitro and in vivo investigations, firocoxib (FX), a second-generation coxib, is a highly selective COX-2 inhibitor in horses. With a COX-1/COX-2 IC50 ratio of 643 in horses, FX spares the COX-1 inhibitory effects. It is approved for the treatment of musculoskeletal problems and lamen...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2023-03-01
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| Series: | Veterinary and Animal Science |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2451943X23000030 |