RT-QuIC detection of chronic wasting disease prion in platelet samples of white-tailed deer

Abstract Background Chronic wasting disease (CWD) is a prion disease of captive and free-ranging cervids. Currently, a definitive diagnosis of CWD relies on immunohistochemistry detection of PrPSc in the obex and retropharyngeal lymph node (RPLN) of the affected cervids. For high-throughput screenin...

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Main Authors: Estela Kobashigawa, Sherri Russell, Michael Z. Zhang, Emily A. Sinnott, Michael Connolly, Shuping Zhang
פורמט: Article
שפה:English
יצא לאור: BMC 2024-04-01
סדרה:BMC Veterinary Research
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גישה מקוונת:https://doi.org/10.1186/s12917-024-04005-y