A straightforward method to quantify circulating mRNAs as biomarkers of colorectal cancer

A straightforward method to quantify circulating mRNAs as biomarkers of colorectal cancer

Abstract Optimizing the biomarker combination to be analyzed in liquid biopsies should improve personalized medicine. We developed a method to purify circulating cell-free mRNAs from plasma samples and to quantify them by RT-qPCR. We selected three candidate colorectal cancer biomarkers (B2M, TIMP-1...

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Bibliographic Details
Main Authors: Marie Grosgeorges, Laurence Picque Lasorsa, Brice Pastor, Corinne Prévostel, Evelyne Crapez, Cynthia Sanchez, Florence Frayssinoux, Marta Jarlier, Véronique Pezzella, Laure Monard, Marc Ychou, Alain R. Thierry, Thibault Mazard, Philippe Blache
Format: Article
Language:English
Published: Nature Portfolio 2023-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-29948-4

Internet

https://doi.org/10.1038/s41598-023-29948-4

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