Radiosensitizing effects of pyrogallol-loaded mesoporous or-ganosilica nanoparticles on gastric cancer by amplified ferroptosis

Radiosensitizing effects of pyrogallol-loaded mesoporous or-ganosilica nanoparticles on gastric cancer by amplified ferroptosis

Radiotherapy (RT) incorporated multidisciplinary treatment is producing excellent clinical results, but its efficacy in treating late-stage gastric cancer is constrained by radioresistance and RT-related toxicity. Especially, since reactive oxygen species are the pivotal effectual molecules of ioniz...

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Bibliographic Details
Main Authors: Hongwei Wang, Hongyan Niu, Xi Luo, Nan Zhu, Jingfeng Xiang, Yan He, Zhian Chen, Guoxin Li, Yanfeng Hu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
gastric cancer
radiosensitivity
ROS generation
GSH depletion
ferroptosis
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2023.1171450/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2023.1171450/full

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