EEG-based grading of immune effector cell-associated neurotoxicity syndrome

EEG-based grading of immune effector cell-associated neurotoxicity syndrome

Abstract CAR-T cell therapy is an effective cancer therapy for multiple refractory/relapsed hematologic malignancies but is associated with substantial toxicity, including Immune Effector Cell Associated Neurotoxicity Syndrome (ICANS). Improved detection and assessment of ICANS could improve managem...

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Main Authors: Daniel K. Jones, Christine A. Eckhardt, Haoqi Sun, Ryan A. Tesh, Preeti Malik, Syed Quadri, Marcos Santana Firme, Meike van Sleuwen, Aayushee Jain, Ziwei Fan, Jin Jing, Wendong Ge, Fábio A. Nascimento, Irfan S. Sheikh, Caron Jacobson, Matthew Frigault, Eyal Y. Kimchi, Sydney S. Cash, Jong Woo Lee, Jorg Dietrich, M. Brandon Westover
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-24010-1

Internet

https://doi.org/10.1038/s41598-022-24010-1

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