Toward sustainable solid-phase peptide synthesis strategy – in situ Fmoc removal

Toward sustainable solid-phase peptide synthesis strategy – in situ Fmoc removal

Solid-phase peptide synthesis (SPPS) is the method of choice for the synthesis of peptides for research and production purposes. Despite having several positive features, it remains a challenge to reduce the amount of solvent waste generated during the synthesis. We proposed a 3-step protocol (in-si...

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Bibliographic Details
Main Authors: Ndumiso Mthethwa, K. P. Nandhini, Ashish Kumar, Anamika Sharma, Beatriz G. de la Torre, Fernando Albericio
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Green Chemistry Letters and Reviews
Subjects:
Fluorenylmethoxycarbonyl (Fmoc)
green chemistry
in situ coupling deprotection
peptide
4-methylpiperidine
sustainable chemistry
Online Access:https://www.tandfonline.com/doi/10.1080/17518253.2024.2325993

Internet

https://www.tandfonline.com/doi/10.1080/17518253.2024.2325993

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