Case report: Neuroendocrine breast carcinoma with a germline EGFR T790M mutation

Case report: Neuroendocrine breast carcinoma with a germline EGFR T790M mutation

BackgroundThe epidermal growth factor receptor (EGFR) p.Thr790Met (T790M) mutation was discovered as a resistance mechanism in patients with lung cancer treated with first- and second-generation tyrosine kinase inhibitors. Further studies revealed the EGFR T790M mutation in treatment-naive non-small...

Full description

Bibliographic Details
Main Authors: Olivia A. Sagan, Anna Rothstein, Bhaghyasree Jambunathan, Mersiha Hadziahmetovic, Anita Antoniolli, M. Hammad Rashid
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Oncology
Subjects:
neuroendocrine breast cancer
germline EGFR T790M mutation
triple-negative breast cancer (TNBC)
EGFR mutation
chemotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1176868/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2023.1176868/full

Similar Items