A Preclinical Embryonic Zebrafish Xenograft Model to Investigate CAR T Cells In Vivo

A Preclinical Embryonic Zebrafish Xenograft Model to Investigate CAR T Cells In Vivo

Chimeric antigen receptor (CAR) T cells have proven to be a powerful cellular therapy for B cell malignancies. Massive efforts are now being undertaken to reproduce the high efficacy of CAR T cells in the treatment of other malignancies. Here, predictive preclinical model systems are important, and...

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Bibliographic Details
Main Authors: Susana Pascoal, Benjamin Salzer, Eva Scheuringer, Andrea Wenninger-Weinzierl, Caterina Sturtzel, Wolfgang Holter, Sabine Taschner-Mandl, Manfred Lehner, Martin Distel
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Cancers
Subjects:
zebrafish xenografts
car t cells
cd19 car
in vivo imaging
Online Access:https://www.mdpi.com/2072-6694/12/3/567

Internet

https://www.mdpi.com/2072-6694/12/3/567

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