Adenosinergic System and BDNF Signaling Changes as a Cross-Sectional Feature of RTT: Characterization of <i>Mecp2</i> Heterozygous Mouse Females

Adenosinergic System and BDNF Signaling Changes as a Cross-Sectional Feature of RTT: Characterization of <i>Mecp2</i> Heterozygous Mouse Females

Rett Syndrome is an X-linked neurodevelopmental disorder (RTT; OMIM#312750) associated to <i>MECP2</i> mutations. MeCP2 dysfunction is seen as one cause for the deficiencies found in brain-derived neurotrophic factor (BDNF) signaling, since BDNF is one of the genes under MeCP2 jurisdicti...

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Bibliographic Details
Main Authors: Catarina Miranda-Lourenço, Jéssica Rosa, Nádia Rei, Rita F. Belo, Ana Luísa Lopes, Diogo Silva, Cátia Vieira, Teresa Magalhães-Cardoso, Ricardo Viais, Paulo Correia-de-Sá, Ana M. Sebastião, Maria J. Diógenes
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:International Journal of Molecular Sciences
Subjects:
Rett syndrome
<i>Mecp2</i> heterozygous females
adenosine
BDNF
Online Access:https://www.mdpi.com/1422-0067/24/22/16249

Internet

https://www.mdpi.com/1422-0067/24/22/16249

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