Using Drosophila to discover mechanisms underlying type 2 diabetes

Mechanisms of glucose homeostasis are remarkably well conserved between the fruit fly Drosophila melanogaster and mammals. From the initial characterization of insulin signaling in the fly came the identification of downstream metabolic pathways for nutrient storage and utilization. Defects in these...

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Bibliographic Details
Main Authors: Ronald W. Alfa, Seung K. Kim
Format: Article
Language:English
Published: The Company of Biologists 2016-04-01
Series:Disease Models & Mechanisms
Subjects:
Online Access:http://dmm.biologists.org/content/9/4/365