Impact of transient down-regulation of DREAM in human embryonic stem cell pluripotency

Little is known about the functions of downstream regulatory element antagonist modulator (DREAM) in embryonic stem cells (ESCs). However, DREAM interacts with cAMP response element-binding protein (CREB) in a Ca2+-dependent manner, preventing CREB binding protein (CBP) recruitment. Furthermore, CRE...

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Bibliographic Details
Main Authors: A. Fontán-Lozano, V. Capilla-Gonzalez, Y. Aguilera, N. Mellado, A.M. Carrión, B. Soria, A. Hmadcha
Format: Article
Language:English
Published: Elsevier 2016-05-01
Series:Stem Cell Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506116000829