Pharmacodynamics, toxicology and toxicokinetics of ropivacaine oil delivery depot

Abstract Background Ropivacaine oil delivery depot (RODD) can be used to treat postoperative incision pain. The aim was to study pharmacodynamics, toxicity and toxicokinetics of RODD. Methods The base research of RODD were conducted. Thirty rabbits were randomly divided into saline, solvent, ropivac...

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Bibliographic Details
Main Authors: Wu-dang Lu, Min-quan Hui, Jing-liang Gu, Li Liu, Man-li Wu, Yi Yang, Yong-xiao Cao
Format: Article
Language:English
Published: BMC 2022-04-01
Series:BMC Anesthesiology
Subjects:
Online Access:https://doi.org/10.1186/s12871-022-01653-1