Study of the active ingredients and mechanism of Sparganii rhizoma in gastric cancer based on HPLC-Q-TOF–MS/MS and network pharmacology

Abstract Sparganii rhizoma (SL) has potential therapeutic effects on gastric cancer (GC), but its main active ingredients and possible anticancer mechanism are still unclear. In this study, we used HPLC-Q-TOF–MS/MS to comprehensively analyse the chemical components of the aqueous extract of SL. On t...

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Bibliographic Details
Main Authors: Xiaona Lu, Yawei Zheng, Fang Wen, Wenjie Huang, Xiaoxue Chen, Shuai Ruan, Suping Gu, Yue Hu, Yuhao Teng, Peng Shu
Format: Article
Language:English
Published: Nature Portfolio 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-81485-0