A recombinant gp145 Env glycoprotein from HIV-1 expressed in two different cell lines: Effects on glycosylation and antigenicity.

A recombinant gp145 Env glycoprotein from HIV-1 expressed in two different cell lines: Effects on glycosylation and antigenicity.

The envelope glycoprotein (Env) of the human immunodeficiency virus (HIV), has been the primary target for the development of a protective vaccine against infection. The extensive N-linked glycosylation on Env is an important consideration as it may affect efficacy, stability, and expression yields....

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Main Authors: José A González-Feliciano, Pearl Akamine, Coral M Capó-Vélez, Manuel Delgado-Vélez, Vincent Dussupt, Shelly J Krebs, Valerie Wojna, Victoria R Polonis, Abel Baerga-Ortiz, José A Lasalde-Dominicci
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0231679

Internet

https://doi.org/10.1371/journal.pone.0231679

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