Mutational profile of KRAS, NRAS, BRAF, PIK3CA, and AKT1 genes in colorectal cancer patients in a tertiary care hospital, Dhaka

Mutational profile of KRAS, NRAS, BRAF, PIK3CA, and AKT1 genes in colorectal cancer patients in a tertiary care hospital, Dhaka

Background: Colorectal carcinoma (CRC) is the third most common cancer in the world and incidences are on the rise in Bangladesh. KRAS, NRAS, BRAF, PIK3CA, and AKTI gene mutations are predictive markers of biological therapies, monoclonal antibodies targeting EGFR. The purpose of this study was to d...

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Bibliographic Details
Main Authors: Sharmin Chowdhury, Sheikh Joly Ferdous Ara, Shirazum Monira Mili, Tahani Momotaz, Md Maruf Ahmed Molla, Shaheda Anwar, Ahmed Abu Saleh
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:Advances in Cancer Biology - Metastasis
Subjects:
CRC
KRAS
NRAS
BRAF
PIK3CA
AKT1
Online Access:http://www.sciencedirect.com/science/article/pii/S2667394022000284

Internet

http://www.sciencedirect.com/science/article/pii/S2667394022000284

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