Integrated Manufacturing of Suspended and Aligned Nanofibrous Scaffold for Structural Maturation and Synchronous Contraction of HiPSC-Derived Cardiomyocytes

Integrated Manufacturing of Suspended and Aligned Nanofibrous Scaffold for Structural Maturation and Synchronous Contraction of HiPSC-Derived Cardiomyocytes

Electrospun nanofiber constructs represent a promising alternative for mimicking the natural extracellular matrix in vitro and have significant potential for cardiac patch applications. While the effect of fiber orientation on the morphological structure of cardiomyocytes has been investigated, fibe...

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Bibliographic Details
Main Authors: Lingling Liu, Feng Xu, Hang Jin, Bin Qiu, Jianhui Yang, Wangzihan Zhang, Qiang Gao, Bin Lin, Songyue Chen, Daoheng Sun
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Bioengineering
Subjects:
hiPSC-derived cardiomyocytes
electrospinning
aligned nanofibers
suspended nanofibers
anisotropic cardiac tissue
maturation
Online Access:https://www.mdpi.com/2306-5354/10/6/702

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https://www.mdpi.com/2306-5354/10/6/702

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