Lack of the hyaluronan receptor CD44 affects the course of bacterial otitis media and reduces leukocyte recruitment to the middle ear

Lack of the hyaluronan receptor CD44 affects the course of bacterial otitis media and reduces leukocyte recruitment to the middle ear

Abstract Background CD44 is a multifunctional molecule that plays major roles in both leukocyte recruitment and tissue proliferation. Since mucosal hyperplasia and leukocyte infiltration of the middle ear cavity are major features of otitis media, we evaluated the role of CD44 in the pathophysiology...

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Bibliographic Details
Main Authors: Hyun Woo Lim, Kwang Pak, Arwa Kurabi, Allen F. Ryan
Format: Article
Language:English
Published: BMC 2019-06-01
Series:BMC Immunology
Subjects:
Middle ear
Infection
Inflammation
Hyaluronan (Hyaluronic acid)
Online Access:http://link.springer.com/article/10.1186/s12865-019-0302-3

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http://link.springer.com/article/10.1186/s12865-019-0302-3

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