Upregulation of Spinal miR-155-5p Contributes to Mechanical Hyperalgesia by Promoting Inflammatory Activation of Microglia in Bone Cancer Pain Rats

Upregulation of Spinal miR-155-5p Contributes to Mechanical Hyperalgesia by Promoting Inflammatory Activation of Microglia in Bone Cancer Pain Rats

Bone cancer pain (BCP) seriously deteriorates the life quality of patients, but its underlying mechanism is still unclear. Spinal microRNAs might contribute to the development of BCP and the role of microglial activation is controversial. In this study, we established a BCP model by injecting Walker...

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Bibliographic Details
Main Authors: Yanping Jian, Zongbin Song, Zhuofeng Ding, Jian Wang, Ruike Wang, Xinran Hou
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Life
Subjects:
bone cancer pain
mechanical hyperalgesia
miR-155-5p
<i>Sgk3</i>
microglia
Online Access:https://www.mdpi.com/2075-1729/12/9/1349

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https://www.mdpi.com/2075-1729/12/9/1349

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