Substrate stiffness-dependent regulatory volume decrease and calcium signaling in chondrocytes

Substrate stiffness-dependent regulatory volume decrease and calcium signaling in chondrocytes

The pericellular matrix stiffness is strongly associated with its biochemical and structural changes during the aging and osteoarthritis progress of articular cartilage. However, how substrate stiffness modulates the chondrocyte regulatory volume decrease (RVD) and calcium signaling in chondrocytes...

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Bibliographic Details
Main Authors: Zhang Min, Wu Xiaoan, Du Genlai, Chen Weiyi, Zhang Quanyou
Format: Article
Language:English
Published: China Science Publishing & Media Ltd. 2021-12-01
Series:Acta Biochimica et Biophysica Sinica
Subjects:
substrate stiffness
regulatory volume decrease
viscoelasticity
calcium signaling
TRPV4
Online Access:https://www.sciengine.com/doi/10.3724/abbs.2021008

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https://www.sciengine.com/doi/10.3724/abbs.2021008

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