CHD4 mediates proliferation and migration of non-small cell lung cancer via the RhoA/ROCK pathway by regulating PHF5A

CHD4 mediates proliferation and migration of non-small cell lung cancer via the RhoA/ROCK pathway by regulating PHF5A

Abstract Background Chromodomain helicase DNA-binding protein 4 (CHD4) has been shown to contribute to DNA repair and cell cycle promotion; however, its roles in cancer initiation and progression remain largely unknown. This study aimed to demonstrate the role of CHD4 in the development of non-small...

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Bibliographic Details
Main Authors: Nuo Xu, Fanglei Liu, Shengdi Wu, Maosong Ye, Haiyan Ge, Meiling Zhang, Yuanlin Song, Lin Tong, Jian Zhou, Chunxue Bai
Format: Article
Language:English
Published: BMC 2020-03-01
Series:BMC Cancer
Subjects:
CHD4
metastasis
non-small cell lung cancer
PHF5A
proliferation
Online Access:http://link.springer.com/article/10.1186/s12885-020-06762-z

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http://link.springer.com/article/10.1186/s12885-020-06762-z

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