Small-Angle X-ray Scattering Models of APOBEC3B Catalytic Domain in a Complex with a Single-Stranded DNA Inhibitor

Small-Angle X-ray Scattering Models of APOBEC3B Catalytic Domain in a Complex with a Single-Stranded DNA Inhibitor

In normal cells APOBEC3 (A3A-A3H) enzymes as part of the innate immune system deaminate cytosine to uracil on single-stranded DNA (ssDNA) to scramble DNA in order to give protection against a range of exogenous retroviruses, DNA-based parasites, and endogenous retroelements. However, some viruses an...

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Bibliographic Details
Main Authors: Fareeda M. Barzak, Timothy M. Ryan, Maksim V. Kvach, Harikrishnan M. Kurup, Hideki Aihara, Reuben S. Harris, Vyacheslav V. Filichev, Elena Harjes, Geoffrey B. Jameson
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Viruses
Subjects:
APOBEC
SAXS
APOBEC3
APOBEC3B
dimer
virus restriction
Online Access:https://www.mdpi.com/1999-4915/13/2/290

Internet

https://www.mdpi.com/1999-4915/13/2/290

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