Results from a Phase 1 Study of Sodium Selenite in Combination with Palliative Radiation Therapy in Patients with Metastatic Cancer

Results from a Phase 1 Study of Sodium Selenite in Combination with Palliative Radiation Therapy in Patients with Metastatic Cancer

In preclinical studies, selenite had single agent activity and radiosensitized tumors in vivo. Here we report results from a Phase 1 trial in 15 patients with metastatic cancer treated with selenite (5.5 to 49.5 mg) orally as a single dose 2 hours before each radiation therapy (RT) treatment. Patien...

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Bibliographic Details
Main Authors: Susan J. Knox, Priya Jayachandran, Christine A. Keeling, Kathryn J. Stevens, Navjot Sandhu, Stacy Leanne Stamps-DeAnda, Rada Savic, Lei Shura, Mark K. Buyyounouski, Kevin Grimes
Format: Article
Language:English
Published: Elsevier 2019-11-01
Series:Translational Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523319303365

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http://www.sciencedirect.com/science/article/pii/S1936523319303365

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