Helicobacter pylori Dampens HLA-II Expression on Macrophages via the Up-Regulation of miRNAs Targeting CIITA

Helicobacter pylori Dampens HLA-II Expression on Macrophages via the Up-Regulation of miRNAs Targeting CIITA

Macrophages have a major role in infectious and inflammatory diseases, and the available data suggest that Helicobacter pylori persistence can be explained in part by the failure of the bacterium to be killed by professional phagocytes. Macrophages are cells ready to kill the engulfed pathogen, thro...

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Bibliographic Details
Main Authors: Gaia Codolo, Marta Toffoletto, Francesco Chemello, Sara Coletta, Gemma Soler Teixidor, Greta Battaggia, Giada Munari, Matteo Fassan, Stefano Cagnin, Marina de Bernard
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Immunology
Subjects:
Helicobacter pylori
miRNA
macrophages
antigen presentation
gastric cancer
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02923/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.02923/full

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