Release of ranibizumab using a porous poly(dimethylsiloxane) capsule suppressed laser-induced choroidal neovascularization via the transscleral route

Abstract The administration of anti-vascular endothelial growth factor drugs in the posterior eye segment with sustained release through less invasive methods is a challenge in the treatment of age-related macular disease. We developed a flexible capsule device using porous poly(dimethylsiloxane) (P...

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Bibliographic Details
Main Authors: Nobuhiro Nagai, Reiko Daigaku, Remi Motoyama, Hirokazu Kaji, Toshiaki Abe
Format: Article
Language:English
Published: Springer 2022-12-01
Series:Journal of Materials Science: Materials in Medicine
Subjects:
Online Access:https://doi.org/10.1007/s10856-022-06705-z