High-throughput screening of spike variants uncovers the key residues that alter the affinity and antigenicity of SARS-CoV-2

High-throughput screening of spike variants uncovers the key residues that alter the affinity and antigenicity of SARS-CoV-2

Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has elicited a worldwide pandemic since late 2019. There has been ~675 million confirmed coronavirus disease 2019 (COVID-19) cases, leading to more than 6.8 million deaths as of March 1, 2023. Five SARS-CoV-2 variants of...

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Bibliographic Details
Main Authors: Yufeng Luo, Shuo Liu, Jiguo Xue, Ye Yang, Junxuan Zhao, Ying Sun, Bolun Wang, Shenyi Yin, Juan Li, Yuchao Xia, Feixiang Ge, Jiqiao Dong, Lvze Guo, Buqing Ye, Weijin Huang, Youchun Wang, Jianzhong Jeff Xi
Format: Article
Language:English
Published: Nature Publishing Group 2023-04-01
Series:Cell Discovery
Online Access:https://doi.org/10.1038/s41421-023-00534-2

Internet

https://doi.org/10.1038/s41421-023-00534-2

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