Unlocking pandemic potential: prevalence and spatial patterns of key substitutions in avian influenza H5N1 in Egyptian isolates

Abstract Background Avian influenza H5N1 has a high human case fatality rate, but is not yet well-adapted to human hosts. Amino acid substitutions currently circulating in avian populations may enhance viral fitness in, and thus viral adaptation to, human hosts. Substitutions which could increase th...

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Bibliographic Details
Main Authors: Sean G. Young, Andrew Kitchen, Ghazi Kayali, Margaret Carrel
Format: Article
Language:English
Published: BMC 2018-07-01
Series:BMC Infectious Diseases
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12879-018-3222-6