Palmitoyl Protein Thioesterase 1 Is Essential for Myogenic Autophagy of C2C12 Skeletal Myoblast

Palmitoyl Protein Thioesterase 1 Is Essential for Myogenic Autophagy of C2C12 Skeletal Myoblast

Skeletal muscle differentiation is an essential process for the maintenance of muscle development and homeostasis. Reactive oxygen species (ROS) are critical signaling molecules involved in muscle differentiation. Palmitoyl protein thioesterase 1 (PPT1), a lysosomal enzyme, is involved in removing t...

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Bibliographic Details
Main Authors: Hyeong Rok Yun, Yong Hwa Jo, Jieun Kim, Ngoc Ngo Yen Nguyen, Yoonhwa Shin, Sung Soo Kim, Tae Gyu Choi
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Physiology
Subjects:
palmitoyl protein thioesterase 1
mitochondrial reactive oxygen species
autophagy
mammalian target of rapamycin complex
muscle differentiation
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2020.569221/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2020.569221/full

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