Human Umbilical Cord Blood Mononuclear Cells Ameliorate CCl4-Induced Acute Liver Injury in Mice via Inhibiting Inflammatory Responses and Upregulating Peripheral Interleukin-22

Human Umbilical Cord Blood Mononuclear Cells Ameliorate CCl4-Induced Acute Liver Injury in Mice via Inhibiting Inflammatory Responses and Upregulating Peripheral Interleukin-22

Background: Human umbilical cord blood mononuclear cells (hUCBMNCs) show therapeutic effects on many inflammatory diseases. The deterioration of acute liver injury is attributed to excessive inflammatory responses triggered by damage-associated molecular patterns (DAMPs) and pathogen-associated mole...

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Bibliographic Details
Main Authors: Jinming Zhang, Hengben Zhai, Pei Yu, Dabao Shang, Ruidong Mo, Ziqiang Li, Xiaolin Wang, Jie Lu, Qing Xie, Xiaogang Xiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Pharmacology
Subjects:
cell therapy
liver injury
liver inflammation
liver regeneration
IL-22
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.924464/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.924464/full

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