Genetic mutation and biological pathway prediction based on whole slide images in breast carcinoma using deep learning

Abstract Breast carcinoma is the most common cancer among women worldwide that consists of a heterogeneous group of subtype diseases. The whole-slide images (WSIs) can capture the cell-level heterogeneity, and are routinely used for cancer diagnosis by pathologists. However, key driver genetic mutat...

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Bibliographic Details
Main Authors: Hui Qu, Mu Zhou, Zhennan Yan, He Wang, Vinod K. Rustgi, Shaoting Zhang, Olivier Gevaert, Dimitris N. Metaxas
Format: Article
Language:English
Published: Nature Portfolio 2021-09-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-021-00225-9