Hippocampal glial inflammatory markers are differentially altered in a novel mouse model of perimenopausal cerebral amyloid angiopathy

Dementia is often characterized by age-dependent cerebrovascular pathology, neuroinflammation, and cognitive deficits with notable sex differences in risk, disease onset, progression and severity. Women bear a disproportionate burden of dementia, and the onset of menopause (i.e., perimenopause) may...

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Bibliographic Details
Main Authors: Jimcy Platholi, Roberta Marongiu, Laibaik Park, Fangmin Yu, Garrett Sommer, Rena Weinberger, William Tower, Teresa A. Milner, Michael J. Glass
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Aging Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2023.1280218/full