Simultaneous Quantification of Trehalose and Trehalose 6-Phosphate by Hydrophilic Interaction Chromatography/Electrospray Accurate Mass Spectrometry with Application in Non-Targeted Metabolomics

Simultaneous Quantification of Trehalose and Trehalose 6-Phosphate by Hydrophilic Interaction Chromatography/Electrospray Accurate Mass Spectrometry with Application in Non-Targeted Metabolomics

High-resolution mass spectrometry (HRMS) was coupled with ultra-high-performance liquid chromatography (UHPLC) to simultaneously quantify trehalose and trehalose 6-phosphate without derivatization or sample preparation. The use of full scan mode and exact mass analysis also makes it possible to carr...

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Bibliographic Details
Main Authors: Ye Tao, Yannick Rossez, Clovis Bortolus, Luminita Duma, Faustine Dubar, Franck Merlier
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Molecules
Subjects:
trehalose
trehalose 6-phosphate
sugar
sugar phosphate
high resolution time-of-flight MS
HILIC
Online Access:https://www.mdpi.com/1420-3049/28/8/3443

Internet

https://www.mdpi.com/1420-3049/28/8/3443

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