High-dose vitamin C on sepsis: Protocol of a prospective, multi-centered, double-blinded, randomized, and placebo-controlled superiority study

High-dose vitamin C on sepsis: Protocol of a prospective, multi-centered, double-blinded, randomized, and placebo-controlled superiority study

BackgroundSepsis is an inflammatory syndrome with life-threatening organ dysfunction and high mortality. In the recent 10 years, high-dose intravenous injection of vitamin C, the first-line antioxidant of humans, has received highlighted attention in the field of critical care. The study aims to exa...

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Bibliographic Details
Main Authors: Bing Zhao, Mengjiao Li, Wenwu Sun, Jian Li, Leshan Liu, Yihui Wang, Silei Sun, Lili Xu, Xing Qi, Mengqi Xie, Yuhua Zhou, Tongtian Ni, Yi Yao, Peili Chen, Meiling Yu, Weisong Jiang, Ning Ning, Huiqiu Sheng, Erzhen Chen, Ruilan Wang, Chaoyang Tong, Yu Cao, Mingwei Sun, Enqiang Mao
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Medicine
Subjects:
high dose
vitaminc
sepsis
antioxidant
clinical trial
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.950246/full

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https://www.frontiersin.org/articles/10.3389/fmed.2022.950246/full

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