Mycobacterium tuberculosis proteins involved in cell wall lipid biosynthesis improve BCG vaccine efficacy in a murine TB model

Mycobacterium tuberculosis proteins involved in cell wall lipid biosynthesis improve BCG vaccine efficacy in a murine TB model

Objectives: Advances in tuberculosis (TB) vaccine development are urgently required to enhance global disease management. We evaluated the potential of Mycobacterium tuberculosis (M. tb)-derived protein antigens Rv0447c, Rv2957 and Rv2958c to boost BCG vaccine efficacy in the presence or absence of...

Full description

Bibliographic Details
Main Authors: Martin Rao, Nathalie Cadieux, Megan Fitzpatrick, Steven Reed, Sergei Arsenian, Davide Valentini, Shreemanta Parida, Ernest Dodoo, Alimuddin Zumla, Markus Maeurer
Format: Article
Language:English
Published: Elsevier 2017-03-01
Series:International Journal of Infectious Diseases
Subjects:
Mycobacterium tuberculosis
tuberculosis
vaccines
Bacille Calmette-Guérin
antigens
T cells
antibodies
Online Access:http://www.sciencedirect.com/science/article/pii/S1201971217300279

Internet

http://www.sciencedirect.com/science/article/pii/S1201971217300279

Similar Items