Mycobacterium tuberculosis proteins involved in cell wall lipid biosynthesis improve BCG vaccine efficacy in a murine TB model

Mycobacterium tuberculosis proteins involved in cell wall lipid biosynthesis improve BCG vaccine efficacy in a murine TB model

Objectives: Advances in tuberculosis (TB) vaccine development are urgently required to enhance global disease management. We evaluated the potential of Mycobacterium tuberculosis (M. tb)-derived protein antigens Rv0447c, Rv2957 and Rv2958c to boost BCG vaccine efficacy in the presence or absence of...

Full description

Bibliographic Details
Main Authors:	Martin Rao, Nathalie Cadieux, Megan Fitzpatrick, Steven Reed, Sergei Arsenian, Davide Valentini, Shreemanta Parida, Ernest Dodoo, Alimuddin Zumla, Markus Maeurer
Format:	Article
Language:	English
Published:	Elsevier 2017-03-01
Series:	International Journal of Infectious Diseases
Subjects:	Mycobacterium tuberculosis tuberculosis vaccines Bacille Calmette-Guérin antigens T cells antibodies
Online Access:	http://www.sciencedirect.com/science/article/pii/S1201971217300279

Similar Items

Inadvertent intramuscular administration of high dose bacillus Calmette Guerin vaccine in a pre-term infant
by: Asima Banu, et al.
Published: (2013-01-01)

Clinical Development of New TB Vaccines: Recent Advances and Next Steps
by: Mark Hatherill, et al.
Published: (2020-01-01)

Vaccination Against Tuberculosis: Revamping BCG by Molecular Genetics Guided by Immunology
by: Stefan H. E. Kaufmann, et al.
Published: (2020-02-01)

CORRELATION BETWEEN COVERAGE OF BCG IMMUNISATION AND HEALTHY HOUSES WITH FINDINGS OF PAEDIATRIC TUBERCULOSIS
by: Melisa Ambarwati
Published: (2019-09-01)

Active and latent tuberculosis in prisoners in the Central-West Region of Brazil
by: Anderson Oliveira Estevan, et al.
Published: (2013-07-01)

Non-Tuberculous Mycobacteria Interference with BCG-Current Controversies and Future Directions
by: Deepshikha Verma, et al.
Published: (2020-11-01)

Association of BMI, diabetes, and risk of tuberculosis: a population-based prospective cohort
by: Peng Lu, et al.
Published: (2021-08-01)

Characterizing the BCG Induced Macrophage and Neutrophil Mechanisms for Defense Against Mycobacterium tuberculosis
by: Thomas E. Bickett, et al.
Published: (2020-06-01)

Commentary: Bettering BCG: a tough task for a TB vaccine?
by: Brahm S. Srivastava, et al.
Published: (2019-09-01)

Next-Generation Vaccines Based on Bacille Calmette–Guérin
by: Natalie E. Nieuwenhuizen, et al.
Published: (2018-02-01)

Activation of M1 Macrophages in Response to Recombinant TB Vaccines With Enhanced Antimycobacterial Activity
by: Shiu-Ju Yang, et al.
Published: (2020-06-01)

A retrospective audit of neonatal BCG vaccination in Grampian, Scotland
by: Saba Savul, et al.
Published: (2023-12-01)

Corrigendum: Activation of M1 Macrophages in Response to Recombinant TB Vaccines With Enhanced Antimycobacterial Activity
by: Shiu-Ju Yang, et al.
Published: (2021-03-01)

Immunogenicity and protective efficacy of recombinant Bacille Calmette-Guerin strains expressing mycobacterium antigens Ag85A, CFP10, ESAT-6, GM-CSF and IL-12p70
by: Fu-Ying Dai, et al.
Published: (2017-06-01)

Gluteal abscess: An unusual complication of Bacille Calmette-Guérin
by: Hakan Buyukoglan, et al.
Published: (2011-01-01)

Mycobacterium bovis Bacille-Calmette-Guérin Infection Aggravates Atherosclerosis
by: Moises A. Huaman, et al.
Published: (2020-12-01)

MTBVAC: Attenuating the Human Pathogen of Tuberculosis (TB) Toward a Promising Vaccine against the TB Epidemic
by: Jesus Gonzalo-Asensio, et al.
Published: (2017-12-01)

The safety of BCG revaccination in the context of COVID-19
by: Adriana Sánchez-García, et al.
Published: (2023-12-01)

Practical considerations for a TB controlled human infection model (TB-CHIM); the case for TB-CHIM in Africa, a systematic review of the literature and report of 2 workshop discussions in UK and Malawi [version 2; peer review: 2 approved, 1 approved with reservations]
by: Keertan Dedha, et al.
Published: (2023-06-01)

Practical considerations for a TB controlled human infection model (TB-CHIM); the case for TB-CHIM in Africa, a systematic review of the literature and report of 2 workshop discussions in UK and Malawi [version 1; peer review: 2 approved, 1 approved with reservations]
by: Keertan Dedha, et al.
Published: (2023-02-01)

HUBUNGAN RIWAYAT STATUS IMUNISASI BACILLE CALMETTE-GUÉRIN (BCG) DENGAN KEJADIAN TUBERKULOSIS (TB) PADA ANAK DI BADAN LAYANAN UMUM DAERAH RUMAH SAKIT UMUM CUT MEUTIA ACEH UTARA TAHUN 2015
by: Hedya Nadhrati Surura, et al.
Published: (2018-02-01)

An Oxygen Supply Strategy for Sonodynamic Therapy in Tuberculous Granuloma Lesions Using a Catalase-Loaded Nanoplatform
by: Hu C, et al.
Published: (2023-11-01)

Cutaneous Tuberculosis- One Diagnosis, a Plethora of Differentials
by: NR Vignesh, et al.
Published: (2022-08-01)

Booster Dose of Bacille Calmette-Guérin Vaccine for Tuberculosis in Low and Middle-Income Countries: A Systematic Review
by: Oduwole OA, et al.
Published: (2021-09-01)

The Natural Effect of BCG Vaccination on COVID-19: The Debate Continues
by: Wenping Gong, et al.
Published: (2022-07-01)

Research progress on specific and non-specific immune effects of BCG and the possibility of BCG protection against COVID-19
by: Jingli Du, et al.
Published: (2023-01-01)

The Recombinant Bacille Calmette–Guérin Vaccine VPM1002: Ready for Clinical Efficacy Testing
by: Natalie E. Nieuwenhuizen, et al.
Published: (2017-09-01)

Identification of Secreted O-Mannosylated Proteins From BCG and Characterization of Immunodominant Antigens BCG_0470 and BCG_0980
by: Guoying Deng, et al.
Published: (2020-03-01)

Heterologous prime-boost BCG with DNA vaccine expressing fusion antigens Rv2299c and Ag85A improves protective efficacy against Mycobacterium tuberculosis in mice
by: Juan Wu, et al.
Published: (2022-10-01)

BCG lymphadenopathy detected in a BCG-vaccinated infant
by: A.S. Barouni, et al.
Published: (2004-05-01)

COVID-19 and Beyond: Exploring Public Health Benefits from Non-Specific Effects of BCG Vaccination
by: Kent J. Koster, et al.
Published: (2021-10-01)

Immunological Interactions between Intestinal Helminth Infections and Tuberculosis
by: Khethiwe Nomcebo Bhengu, et al.
Published: (2022-11-01)

Association Between Antibiotic Treatment and the Efficacy of Intravesical BCG Therapy in Patients With High-Risk Non-Muscle Invasive Bladder Cancer
by: Sahyun Pak, et al.
Published: (2021-04-01)

Bacillus Calmette-Guérin (BCG)-Vaccine Is it giving a protection against SARS-CoV-2?
by: Mehnaz Tanveer, et al.
Published: (2022-06-01)

Bacille Calmette-Guérin Site Reactivation of Kawasaki Disease in Infants under 3 Months of Age: Relation with Diagnosis and Prognosis
by: Da Eun Roh, et al.
Published: (2022-06-01)

Synergistic antibacterial effects of ultrasound combined nanoparticles encapsulated with cellulase and levofloxacin on Bacillus Calmette-Guérin biofilms
by: Zhifei Zhang, et al.
Published: (2023-03-01)

Bilateral symmetrical corneal melting following intravesical Bacille Calmette-Guerin therapy for bladder carcinoma
by: Chandana Chakraborty, et al.
Published: (2012-01-01)

Safety and Immunogenicity of Recombinant <i>Bacille Calmette-Guérin</i> Strain VPM1002 and Its Derivatives in a Goat Model
by: Julia Figl, et al.
Published: (2023-03-01)

Elevated IgG Responses in Infants Are Associated With Reduced Prevalence of Mycobacterium tuberculosis Infection
by: Erin Logan, et al.
Published: (2018-07-01)

The BCG Vaccine for COVID-19: First Verdict and Future Directions
by: Maria Gonzalez-Perez, et al.
Published: (2021-03-01)