Human perivascular stem cell-derived extracellular vesicles mediate bone repair

Human perivascular stem cell-derived extracellular vesicles mediate bone repair

The vascular wall is a source of progenitor cells that are able to induce skeletal repair, primarily by paracrine mechanisms. Here, the paracrine role of extracellular vesicles (EVs) in bone healing was investigated. First, purified human perivascular stem cells (PSCs) were observed to induce mitoge...

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Bibliographic Details
Main Authors: Jiajia Xu, Yiyun Wang, Ching-Yun Hsu, Yongxing Gao, Carolyn Ann Meyers, Leslie Chang, Leititia Zhang, Kristen Broderick, Catherine Ding, Bruno Peault, Kenneth Witwer, Aaron Watkins James
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-09-01
Series:eLife
Subjects:
pericyte
mesenchymal stem cell
exosome
osteogenesis
bone tissue engineering
bone repair
Online Access:https://elifesciences.org/articles/48191

Internet

https://elifesciences.org/articles/48191

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