Coumarin linked to 2-phenylbenzimidazole derivatives as potent α-glucosidase inhibitors

Abstract α-Glucosidase inhibitors have emerged as crucial agents in the management of type 2 diabetes mellitus. In the present study, a new series of coumarin-linked 2-phenylbenzimidazole derivatives 5a–m was designed, synthesized, and evaluated as anti-α-glucosidase agents. Among these derivatives,...

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Bibliographic Details
Main Authors: Mina Sadeghi Ganjeh, Ali Mazlomifar, Ashraf Sadat Shahvelayti, Shiva Khalili Moghaddam
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-024-57673-z