Changes in Oxygen Availability during Glucose-Limited Chemostat Cultivations of <i>Penicillium chrysogenum</i> Lead to Rapid Metabolite, Flux and Productivity Responses
Bioreactor scale-up from the laboratory scale to the industrial scale has always been a pivotal step in bioprocess development. However, the transition of a bioeconomy from innovation to commercialization is often hampered by performance loss in titer, rate and yield. These are often ascribed to tem...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-01-01
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Series: | Metabolites |
Subjects: | |
Online Access: | https://www.mdpi.com/2218-1989/12/1/45 |