Changes in Oxygen Availability during Glucose-Limited Chemostat Cultivations of <i>Penicillium chrysogenum</i> Lead to Rapid Metabolite, Flux and Productivity Responses

Bioreactor scale-up from the laboratory scale to the industrial scale has always been a pivotal step in bioprocess development. However, the transition of a bioeconomy from innovation to commercialization is often hampered by performance loss in titer, rate and yield. These are often ascribed to tem...

Full description

Bibliographic Details
Main Authors: Qi Yang, Wenli Lin, Jiawei Xu, Nan Guo, Jiachen Zhao, Gaoya Wang, Yongbo Wang, Ju Chu, Guan Wang
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Metabolites
Subjects:
Online Access:https://www.mdpi.com/2218-1989/12/1/45