Screening for Rare Mitochondrial Genome Variants Reveals a Potentially Novel Association between <i>MT-CO1</i> and <i>MT-TL2</i> Genes and Diabetes Phenotype

Screening for Rare Mitochondrial Genome Variants Reveals a Potentially Novel Association between <i>MT-CO1</i> and <i>MT-TL2</i> Genes and Diabetes Phenotype

Variations in several nuclear genes predisposing humans to the development of MODY diabetes have been very well characterized by modern genetic diagnostics. However, recent reports indicate that variants in the mtDNA genome may also be associated with the diabetic phenotype. As relatively little res...

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Bibliographic Details
Main Authors: Tomasz Płoszaj, Sebastian Skoczylas, Karolina Gadzalska, Paulina Jakiel, Ewa Juścińska, Monika Gorządek, Agnieszka Robaszkiewicz, Maciej Borowiec, Agnieszka Zmysłowska
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:International Journal of Molecular Sciences
Subjects:
mtDNA
heteroplasmic
diabetes
pathogenic
Online Access:https://www.mdpi.com/1422-0067/25/4/2438

Internet

https://www.mdpi.com/1422-0067/25/4/2438

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