The case for selection at CCR5-Delta32.

The case for selection at CCR5-Delta32.

The C-C chemokine receptor 5, 32 base-pair deletion (CCR5-Delta32) allele confers strong resistance to infection by the AIDS virus HIV. Previous studies have suggested that CCR5-Delta32 arose within the past 1,000 y and rose to its present high frequency (5%-14%) in Europe as a result of strong posi...

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Bibliographic Details
Main Authors: Pardis C Sabeti, Emily Walsh, Steve F Schaffner, Patrick Varilly, Ben Fry, Holli B Hutcheson, Mike Cullen, Tarjei S Mikkelsen, Jessica Roy, Nick Patterson, Richard Cooper, David Reich, David Altshuler, Stephen O'Brien, Eric S Lander
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2005-11-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC1275522?pdf=render

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http://europepmc.org/articles/PMC1275522?pdf=render

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