Maternal malaria induces a procoagulant and antifibrinolytic state that is embryotoxic but responsive to anticoagulant therapy.

Maternal malaria induces a procoagulant and antifibrinolytic state that is embryotoxic but responsive to anticoagulant therapy.

Low birth weight and fetal loss are commonly attributed to malaria in endemic areas, but the cellular and molecular mechanisms that underlie these poor birth outcomes are incompletely understood. Increasing evidence suggests that dysregulated hemostasis is important in malaria pathogenesis, but its...

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Bibliographic Details
Main Authors: John W Avery, Geoffrey M Smith, Simon O Owino, Demba Sarr, Tamas Nagy, Stephen Mwalimu, James Matthias, Lauren F Kelly, Jayakumar S Poovassery, Joab D Middii, Carlos Abramowsky, Julie M Moore
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3274552?pdf=render

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http://europepmc.org/articles/PMC3274552?pdf=render

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